Flash Card 2 Osteolysis
Phagocytes (Macrophage ) engulf debris .
Release of TNF-alpha , TGF-beta ,PDGF
Activate RANK or Osteoblast
https://www.researchgate.net/figure/Hypothetical-model-of-BDNF-and-PTX3-induced-osteolysis-in-bone-metastatic-gastric-cancer_fig5_305689959
Release of TNF-alpha , TGF-beta ,PDGF
Activate RANK or Osteoblast
https://www.researchgate.net/figure/Hypothetical-model-of-BDNF-and-PTX3-induced-osteolysis-in-bone-metastatic-gastric-cancer_fig5_305689959
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